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Selank is a synthetic 7-amino-acid peptide studied for its proposed effects on anxiety-related pathways, stress responses, and cognitive function. This product is for laboratory research only—not for human or veterinary use.
For laboratory research only. Not for human or animal consumption.
VIP Peptides · Research Compound
Selank is a synthetic heptapeptide developed in Russia as an analog
of tuftsin. It has been studied for proposed effects on anxiety-related
pathways, stress responses, and cognitive function.
Product Information
Selank is a synthetic heptapeptide with the sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is described as
a tuftsin analog stabilized by the addition of a Pro-Gly-Pro tail.
Proposed mechanisms under study include effects on enzymes involved
in enkephalin breakdown, GABA-related signaling, serotonin
metabolism, BDNF expression, and immune-related pathways in the
brain. These mechanisms remain research hypotheses.
| Product | Selank |
|---|---|
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Peptide length | 7 amino acids |
| Related peptide | Tuftsin |
| Proposed research areas | Anxiety-related pathways, stress, and cognition |
| Product form / quantity | Confirm against the product label |
Research Areas
Some controlled Russian studies in adults with generalized anxiety
disorder or neurasthenia reported reduced anxiety symptoms. The
findings are based largely on relatively small studies and have not
been robustly replicated in large independent Western trials.
Preclinical research has examined possible stress-protective effects
and changes in neurochemical signaling. These findings do not
establish a treatment benefit in people.
Some studies have described possible anti-asthenic effects and mild
cognitive findings. Evidence is limited, and effects in healthy
individuals or with long-term use are not well characterized.
Laboratory and animal research has explored possible effects on
BDNF expression and immune-related signaling in the brain. These
early findings require further study.
Evidence Overview
Most human evidence described in the source material comes from
Russian clinical studies. Large independent Western randomized
controlled trials are lacking, and the findings have not been
robustly replicated across different populations and settings.
No standardized U.S. dose is established. This page does not provide
preparation, dosing, or administration instructions.
Safety & Regulatory Status
Selank is generally described as well tolerated in the limited studies
available. Mild nasal irritation has been reported with intranasal use.
Claims that it avoids sedation, dependence, or cognitive effects should
not be generalized beyond the specific studies and formulations examined.
Long-term safety outside the available Russian clinical experience is
not well established. In the United States, Selank is not FDA-approved
for any indication. FDA has identified potential concerns for
compounded selank acetate, including immunogenicity risks related to
aggregation and peptide impurities, and has noted gaps in human safety
information.
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